Principal Investigator
1. validatioNN Award by Novo Nordisk, 350.000 CNY, 2023
2. Excellent Young Scientists Fund (Hong Kong and Macau) by the National Natural Science Foundation of China, 2,000,000 CNY, 2023
3. Innovation and Technology Support Programme (Mid-stream, theme-based), Dissecting the therapeutic role of 3A2 antibody for the treatment of Obesity and Type 2 Diabetes,HKD 3,600,000 (in the capacity of PC) (ongoing)
4. Health and Medical Research Fund (HMRF), Investigating the role of ADAM9 in the regulation of body weight and food intake, 2021-2024, HKD1,500,000 (ongoing)
5. Guangdong Natural Science Foundation (General Program), To investigate the role of MT1-MMP in the regulation of insulin sensitivity in non-human primate, 2021-2023, RMB100,000 (ongoing)
6. General Research Fund (GRF), To investigate the role of klotho shedding in the ageing process, 2020-2023, HKD1,195,542 (ongoing)
7. Guangdong Natural Science Foundation (General Program), Investigating the influence of gut microbiome on intestinal stem cells in irritable bowel syndrome, 2019-2021, RMB100,000 (ongoing)
8. General Research Fund (GRF), Investigating the role of MT1-MMP in the regulation of insulin sensitivity and the therapeutic potential of MT1-MMP inhibition in Type 2 diabetes mellitus, 2019-2022, HKD1,037,200 (ongoing)
9. Health and Medical Research Fund (HMRF), Exploring the regulatory role of MT1-MMP for body weight and the therapeutic potential of MT1-MMP inhibition in obesity, 2019-2021, HKD1,500,000 (ongoing)
10. National Natural Science Fund (Young Scientists Fund), Investigating the regulatory role for MT1-MMP in the tumor associated macrophages and tumor lymphangiogenesis, 2019-2021, RMB220,000 (ongoing)
Co-Investigator
1. Young Collaborative Research Fund (YCRF), Mechanistic and therapeutic study on the SARS-CoV-2 reprogramed host tyrosine metabolism and epigenetic regulation, HKD5,000,000 (pending)
2. Collaborative Research Fund (CRF), Longitudinal analysis of gut microbiome and metabolome for the identification of clinical biomarkers for Irritable Bowel Syndrome, HKD10,000,000 (pending)
3. General Research Fund (GRF), Investigating the regulatory role of phenethylamine for serotonin production in the pathogenesis of diarrhea-predominant Irritable Bowel Syndrome, 2022-2024, HKD1,148,982 (ongoing)
4. Health and Medical Research Fund (HMRF), WNT974 and artesunate exhibit synergy in inhibiting colorectal cancer growth by increasing KRAS protein degradation, 2022-2025, HKD1,151,520 (ongoing)
5. General Research Fund (GRF), Gut dysbiosis disrupts stem cell functions via NGF/TrkA signaling pathway in diarrhea-predominant irritable bowel syndrome, 2020-2023, HKD1,195,542 (ongoing)
6. National Natural Science Fund (General Program), MT1-MMP regulates neural stem cells self-renewal and differentiation via Notch signaling, 2013-2016, RMB800,000 (completed)
Internally funded projects
1. External Grant Preparation Support Fund for CRF application (HKBU), The role of MT1-MMP in age-related impairments in cognitive function, 2021-2022 (ongoing)
2. Faculty Research Grants II (HKBU), Nuclear MT1-MMP suppresses TNF-α/NF-κB signaling axis in macrophages, 2018-2019, HKD100,000 (completed)
3. Faculty Research Grants I (HKBU), MT1-MMP regulates body weight through GDF15 signaling, 2018-2019, HKD50,000 (completed)
4. Faculty Research Grants I (HKBU), The function of NGF signaling in the maintenance of intestinal stem cells and their differentiations, 2017-2018, HKD50,000 (completed)
5. Small Project Fund (HKU), The Biological Functions of MT1-MMP in Lymphatic Vascular Development, 2015-2016, HKD50,000 (completed)